Short definitions for terms on this site.
For a clinician. A brief bedside screen of attention, memory, language, visuospatial skill, and orientation. Clinicians use the total and domain scores as a screen.
For a general reader. A short set of thinking tasks. A lower score means more trouble with those tasks.
For a clinician. A clinical syndrome: cognitive decline beyond typical aging, with largely preserved independence.
For a general reader. A person notices more thinking trouble than before, but still handles most daily life. Some people later develop dementia.
For a clinician. An ordered severity band in the published cascade analysis. Tiers group similar domain profiles for progression models.
For a general reader. A step on a ladder of how hard the thinking tasks have become. Nearby steps look alike.
For a clinician. A published sequence of cascade tiers that a group can follow over time. It is a group pattern.
For a general reader. A common route that a group of scores can take as they get worse.
For a clinician. A model that maps a plasma p-tau value onto an estimated disease-time axis.
For a general reader. A way to read a blood tau test as a point on a timeline.
For a clinician. A gene-expression class for colorectal cancer (CMS1 to CMS4). The 62-gene panel paper uses this system.
For a general reader. A label for how a bowel cancer looks in its genes. Doctors use the label to group similar tumours.
For a clinician. A biomarker scheme that marks amyloid (A), tau (T), and neurodegeneration (N) as positive or negative.
For a general reader. A three-part blood or scan checklist for Alzheimer biology: amyloid, tau, and brain-cell loss.
For a clinician. A statistical method that reduces scanner or batch effects while it keeps biological contrast.
For a general reader. A way to make measurements from different machines more comparable.
For a clinician. A wrapper that turns a point prediction into a set with a stated coverage under exchangeability.
For a general reader. A method that gives a range and states how often that range should cover the truth.